VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Phospholipid composition of high density lipoproteins in hyperalphalipoproteinemia

   
Torkhovskaia T.I., Koldaeva A.P., Kurchatova S.A., Titov V.N., Gerasimova E.N.
PubMed Id: 202089
Year: 1977  Volume: 23  Issue: 6  Pages: 768-773
Content of lecithin as related to the total content of phospholipids was increased in alpha-lipoproteins of healthy men with hyper-alpha-lipoproteinemia (concentration of cholesterol exceeded 72 mg% in the lipoproteins). The alpha-lipoproteins accumulated considerably more free cholesterol than its esters; this caused a decrease in the molar ration "phospholipids/free cholesterol". The surface of phospholipid-cholesterol monolayer of alpha-lipoproteins is apparently responsible for retaining of increased amounts of cholesterol in the complex as well as for participation of these structures in enzymatic reactions in blood serum.
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Torkhovskaia, T. I., Koldaeva, A. P., Kurchatova, S. A., Titov, V. N., Gerasimova, E. N. (1977). Phospholipid composition of high density lipoproteins in hyperalphalipoproteinemia. Voprosy Meditsinskoi Khimii, 23(6), 768-773.
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