VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Microsomal oxygenase enzyme system during chronic administration of 2-acetylaminofluorene

   
Kobliakov V.A., Koliada A.Yu.
PubMed Id: 96595
Year: 1978  Volume: 24  Issue: 1  Pages: 113-118
Alteration in content of enzymatic components was studied in microsomal oxygenases system of rats administered with 2-acetyl aminofluorene. Content of cytochrome R-450 was decreased beginning from the fourth week of the experiment. Activity of NADP cytochrome c reductase was higher in animals, treated with the drug as compared with controls. Inductors of the I and II type were capable to induce the enzymatic system up to the end of the experiment - within 16 weeks as far as liver tumors developed.
Download PDF:  
Citation:

Kobliakov, V. A., Koliada, A. Yu. (1978). Microsomal oxygenase enzyme system during chronic administration of 2-acetylaminofluorene. Voprosy Meditsinskoi Khimii, 24(1), 113-118.
References
 1984 (vol 30)
 1983 (vol 29)
 1982 (vol 28)
 1981 (vol 27)
 1980 (vol 26)
 1979 (vol 25)
 1978 (vol 24)
 1977 (vol 23)
 1976 (vol 22)
 1975 (vol 21)
 1974 (vol 20)
 1973 (vol 19)
 1972 (vol 18)
 1971 (vol 17)
 1970 (vol 16)
 1969 (vol 15)
 1968 (vol 14)
 1967 (vol 13)
 1966 (vol 12)
 1965 (vol 11)
◄        ►