VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Intensity of the metabolism of separate brain phospholipid fractions in hyperphenylalaninemia

   
Zuber V.L.
PubMed Id: 664439
Year: 1978  Volume: 24  Issue: 2  Pages: 163-166
Effect of acute and chronic forms of hyperphenylalaninemia on intensity of metabolism and content of some phospholipid fractions was studied in brain of growing rats. Acute form of hyperphenylalaninemia caused a decrease in metabolic activity of phospholipids but did not affect their content. In chronic hyperphenylalaninemia more distinct alterations in brain phospholipids metabolism were manifested as a decrease in their content and in their metabolic intensity. The data obtained suggest that brain demyelination developed in chronic hyperphenylalaninemia.
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Reference:

Zuber V.L. (1978) Voprosy meditsinskoi khimii, 24(2), 163-166.
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