VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Effect of eserine on DNA synthesis in rat liver

   
Elaeva N.L., Stroikov Yu.N.
PubMed Id: 685189
Year: 1978  Volume: 24  Issue: 4  Pages: 461-464
Incorporation of labelled precursors into total and nuclear DNA of liver tissue was inhibited after administration into animals of eserine at a dose 0.1--0.2 mg/100 g of body weight. Simultaneously, DNAase activity was increased and cholinesterase activity was inhibited in liver tissue. The DNA synthesis was inhibited in liver slices, if they were incubated with 2.10(-6) M eserine. The DNAase activity was unaltered in vitro. A cholinolytic compound metacin, pre-administered into the animals, was ineffective at dose of 1 mg/kg; it slightly decreased the effect of eserine at dose of 0.25 mg/kg.
Download PDF:  
Citation:

Elaeva, N. L., Stroikov, Yu. N. (1978). Effect of eserine on DNA synthesis in rat liver. Voprosy Meditsinskoi Khimii, 24(4), 461-464.
References
 1984 (vol 30)
 1983 (vol 29)
 1982 (vol 28)
 1981 (vol 27)
 1980 (vol 26)
 1979 (vol 25)
 1978 (vol 24)
 1977 (vol 23)
 1976 (vol 22)
 1975 (vol 21)
 1974 (vol 20)
 1973 (vol 19)
 1972 (vol 18)
 1971 (vol 17)
 1970 (vol 16)
 1969 (vol 15)
 1968 (vol 14)
 1967 (vol 13)
 1966 (vol 12)
 1965 (vol 11)
◄        ►