VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Effect of phosphatidylserine on formation and lysis of fibrin

   
Byshevskiĭ A.Kh., Lapusova T.M., Mukhacheva I.A.
PubMed Id: 150701
Year: 1978  Volume: 24  Issue: 4  Pages: 510-514
Phosphatidyl serine inhibited non-enzymatic step of fibrin formation (selfassociation of monomeric fibrin). But phosphatidyl serine did not affect the factor XIII activity, the rate of fibrin clot retraction and its tolerance to plasmin. Activity of plasmin was not altered in presence of phosphatidyl serine but influence of slowly acting antiplasmin on plasmin was slightly limited by the lipoid. Due to this phenomenon phosphatidyl serine caused the activation of fibrinolysis in native system (blood plasma). The data obtained support the earlier advanced assumptions on inhibition of thrombin-fibrinogene reaction by phosphatidyl serine.
Download PDF:
Reference:

Byshevskiĭ A.Kh., Lapusova T.M., Mukhacheva I.A. (1978) Voprosy meditsinskoi khimii, 24(4), 510-514.
References
 1984 (vol 30)
 1983 (vol 29)
 1982 (vol 28)
 1981 (vol 27)
 1980 (vol 26)
 1979 (vol 25)
 1978 (vol 24)
 1977 (vol 23)
 1976 (vol 22)
 1975 (vol 21)
 1974 (vol 20)
 1973 (vol 19)
 1972 (vol 18)
 1971 (vol 17)
 1970 (vol 16)
 1969 (vol 15)
 1968 (vol 14)
 1967 (vol 13)
 1966 (vol 12)
 1965 (vol 11)
        

© Institute of Biomedical Chemistry, Moscow, Russia