VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

State of protein and mineral metabolism following thyrocalcitonin administration during experimental osteogenesis

   
Khomullo G.V., Travkina V.M., Ryzhova T.I., Kokoreva G.A.
PubMed Id: 706253
Year: 1978  Volume: 24  Issue: 5  Pages: 613-617
Prolonged administration of thyrocalcitonine (TC) into rats (at a dose 5 un per animal) led to some alterations in protein and mineral metabolism: decrease in content of calcium and phosphorus in blood, activation of alkaline phosphatase in blood, decrease in excretion of hydroxyproline, increase in excretion of aminonitrogen with urine. Distinct correlation was observed between the metabolic activity and definite steps in reparative osteogenesis. Exogenous TC activated the cellular structures, which participated in the regenerative processes, promoted the rapid turnover of bone generation and decreased the periods of tracture healing.
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Khomullo, G. V., Travkina, V. M., Ryzhova, T. I., Kokoreva, G. A. (1978). State of protein and mineral metabolism following thyrocalcitonin administration during experimental osteogenesis. Voprosy Meditsinskoi Khimii, 24(5), 613-617.
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