VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Interrelationship between excretion of cholesterol with urine in oncologic patients and some hormone-metaboloc patterns as well as effect of drugs on these processes

   
Bershteĭn L.M., Tsyrlina E.V., Semiglazov V.F., Valdina E.A., Lvovich E.G.
PubMed Id: 220799
Year: 1979  Volume: 25  Issue: 2  Pages: 144-148
Excretion of cholesterol with urine was studied using gas chromatography in healthy persons, in patients with cancer of mammary glands, fibroadenoma, lung carcinoma and in patients with beningn processes in lungs. Cholesterol excretion was not increased in patients with the malignant tumors studied. In patients with the cancer of mammary glands and lung carcinoma normal correlation was altered between excretion of cholesterol with urine and content of lipoproteins, protein-bound iodine, 11-hydroxycorticosteroids in blood as well as excretion of cyclic AMP with urine. Treatment with euphylline was accompanied by a decrease in cholesteroluria in patients with fibroadenoma but the drug had no comparable effect on patients with the cancer of mammary glands. In patients with the cancer of mammary glands phenphormine caused distinct decrease and misclerone--moderate increase in excretion of cholesterol with urine
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Bershteĭn, L. M., Tsyrlina, E. V., Semiglazov, V. F., Valdina, E. A., Lvovich, E. G. (1979). Interrelationship between excretion of cholesterol with urine in oncologic patients and some hormone-metaboloc patterns as well as effect of drugs on these processes. Voprosy Meditsinskoi Khimii, 25(2), 144-148.
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