VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Type A and B monoamine oxidase activity in hyperbaric oxygenation

   
Goroshinskaia I.A.
PubMed Id: 452501
Year: 1979  Volume: 25  Issue: 3  Pages: 328-333
Substrate specificity of monoamine oxidase (MAO) of the A type from rat brain and liver tissues was altered after exposure of rats to an increased oxygen pressure [4 ati O2, 1 hr]. Simultaneously with a decrease in monoamine deaminating activity the enzyme acquired an ability to deaminate several substances, which are not MAO substrates in normal state, in particular, aminosugars. Activity of MAO of the B type was not altered in brain under hyperoxia. Alterations in catalytic properties of MAO of the A type were apparently important in development of the oxygen intoxication
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Goroshinskaia, I. A. (1979). Type A and B monoamine oxidase activity in hyperbaric oxygenation. Voprosy Meditsinskoi Khimii, 25(3), 328-333.
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