VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Effect of light deprivation on GABA metabolism in subcellular fractions of the rabbit visual system

   
Kunert E., Dovedova E.L.
PubMed Id: 473689
Year: 1979  Volume: 25  Issue: 4  Pages: 460-466
Specific activity of glutamate decarboxylase was decreased in subfractions of light and heavy synaptosomes, and gamma-aminobutyric acid (GABA) transaminase activity--also in subfractions of free mitochondria, isolated from visual zone of brain cortex and of anterior mesencephalon but not from locomotive region of brain cortex of the light-deprived rabbits. Decrease in the ratio GABA transaminase/glutamate decarboxylase indicated distinct inhibition of GABA degradation as compared with its synthesis due to absence of sensory impulsation within the early periods of postnatal ontogenesis of the animals
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Kunert, E., Dovedova, E. L. (1979). Effect of light deprivation on GABA metabolism in subcellular fractions of the rabbit visual system. Voprosy Meditsinskoi Khimii, 25(4), 460-466.
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