A review is presented on the transport of phospholipids between subcellular membranes and participation of specific intracellular lipoproteins in this process. Formation of the protein-lipid complex is specific in relation to both protein and phospholipid. The rate of turnover of various phospholipids is dissimilar in membranes; the most intensive transport of phospholipids occurs across the outer surface of the membranes. The most important properties of the phospholipid transferases are discussed and their specificity in the transport of various phospholipids is considered. Role of these proteins in differentiation of phospholipids in membranes of tiumoral cells, significance for simulation of the phospholipid composition of biomembranes in their reconstruction are also discussed.