VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Increase in DNAase activity in rat urine after intraperitoneal administration of DNAases

   
Khursin N.E.
PubMed Id: 6792773
Year: 1981  Volume: 27  Issue: 2  Pages: 175-178
After intraperitoneal administration of DNAase into rats maximal increase in the enzymatic activity was observed in urine within 3-4 hrs. This suggests the ability of DNAase to penetrate through cell barriers without a loss of its biological activity. The importance of the phenomenon is discussed considering possible use of DNAases as protector of the body against heterologous nucleic acids.
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Khursin, N. E. (1981). Increase in DNAase activity in rat urine after intraperitoneal administration of DNAases. Voprosy Meditsinskoi Khimii, 27(2), 175-178.
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