VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Penetration of the heparin-thromboplastin complex into brain tissues after administration of the complex into healthy animals and into animals with the prethrombotic state caused by atherogenic diet

   
Liapina L.A., Ul'ianov A.M., Bazaz'ian G.G., Boneva Zh.S.
PubMed Id: 7281557
Year: 1981  Volume: 27  Issue: 2  Pages: 181-185
The possibility of heparin penetration into brain cells was shown. The penetration occurred apparently in the form of heparin complexes with thromboplastin. The intensity of penetration depended on the functional state of the anticoagulation system. Accumulation of 35S-heparin and of its complex with thromboplastin was distinctly limited in brain tissue of animals with depression of the anticoagulation system followed the long-term maintaining of the animals on an atherogenic diet.
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Liapina, L. A., Ul'ianov, A. M., Bazaz'ian, G. G., Boneva, Zh. S. (1981). Penetration of the heparin-thromboplastin complex into brain tissues after administration of the complex into healthy animals and into animals with the prethrombotic state caused by atherogenic diet. Voprosy Meditsinskoi Khimii, 27(2), 181-185.
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