VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Oxidative phosphorylation in pulmonary mitochondria after massive blood loss and restitution by autologous transfusion

   
Zeliak V.I., Chumakov V.N.
PubMed Id: 6896251
Year: 1982  Volume: 28  Issue: 2  Pages: 70-75
A procedure is described for isolation and polarographic study of rabbit lung mitochondria exhibiting high respiratory control as well as coupling of oxidation and phosphorylation approaching the theoretical value. The procedure enabled to detect a reversible impairment of respiratory and phosphorylating functions of lung mitochondria under conditions of haemorrhagic shock, which was the most distinct within the first hours after blood reinfusion. Correlation was established between dynamics of alterations in mitochondrial energy production in lung tissue within posthaemorrhagic period and structure-functional characteristics of the lung surface system.
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Zeliak, V. I., Chumakov, V. N. (1982). Oxidative phosphorylation in pulmonary mitochondria after massive blood loss and restitution by autologous transfusion. Voprosy Meditsinskoi Khimii, 28(2), 70-75.
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