VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Analysis of lytic effect on fibrin of immobilized heparin in complex with plasma proteins

   
Platé N.A., Valuev L.I., Gumirova F.Kh., Maklakova I.A.
PubMed Id: 6217639
Year: 1982  Volume: 28  Issue: 5  Pages: 19-23
Reactions of heparin, covalently immobilized in hydrogel, with fibrinolysin, blood serum albumin, thrombin and fibrinogen were studied. All the proteins studied were shown to penetrate into the hydrogel pores and to interact with the immobilized heparin. Stability of the complexes was decreased in the following sequence: fibrinogen = thrombin much greater than fibrinolysin much greater than blood serum albumin. Complexes of the immobilized heparin with fibrinogen, thrombin and fibrinolysin hydrolyzed the unstabilized fibrin.
Download PDF:
Reference:

Platé N.A., Valuev L.I., Gumirova F.Kh., Maklakova I.A. (1982) Voprosy meditsinskoi khimii, 28(5), 19-23.
References
 1984 (vol 30)
 1983 (vol 29)
 1982 (vol 28)
 1981 (vol 27)
 1980 (vol 26)
 1979 (vol 25)
 1978 (vol 24)
 1977 (vol 23)
 1976 (vol 22)
 1975 (vol 21)
 1974 (vol 20)
 1973 (vol 19)
 1972 (vol 18)
 1971 (vol 17)
 1970 (vol 16)
 1969 (vol 15)
 1968 (vol 14)
 1967 (vol 13)
 1966 (vol 12)
 1965 (vol 11)
        

© Institute of Biomedical Chemistry, Moscow, Russia