VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Excretion of catecholamines and lipid composition of blood in patients with chronic pancreatitis

   
Frolova I.A., Tsagikian T.A., Borisova L.I., Gordeeva V.A., Sirota I.I.
PubMed Id: 6407200
Year: 1983  Volume: 29  Issue: 2  Pages: 127-130
Excretion of adrenaline was increased in patients with chronic recurrent pancreatitis, excretion of noradrenaline tended to decrease although the content of this amine exceeded 1.5-2-fold its normal concentration in individual patients; excretion of DOPA was unaltered. Hyperlipoproteinemia was found in the majority of the patients. Maximal level of the adrenaline excretion was mainly observed in the patients with high activity of the trypsin inhibitor in blood serum as well as with the high ratio trypsin inhibitor/trypsin. An increase in the adrenaline excretion correlated with hypercholesterolemia and to a lesser extent--with hypertriglyceridemia. The most pronounced hypertriglyceridemia was typical for the patients with alcoholic abuse. Relationship between catecholamines and extrasecretory functions of pancreatic gland as well as with hyperlipoproteinemia in pancreatitis is discussed. An increase in the total antitryptic activity might be caused by activation of the sympathoadrenal system or by hyperproduction of adrenaline.
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Frolova I.A., Tsagikian T.A., Borisova L.I., Gordeeva V.A., Sirota I.I. (1983) Voprosy meditsinskoi khimii, 29(2), 127-130.
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