VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Content of middle mass molecules in blood serum of patients with burns after hemosorption treatment

   
Markelov I.M., Vikhriev B.S., Tupikova Z.A., Kuznetsova L.A.
PubMed Id: 6880111
Year: 1983  Volume: 29  Issue: 3  Pages: 105-108
Content of so-called "middle mass molecules" in blood serum of patients with acute burn toxemia was studied by means of gel filtration on Sephadex G-25. Acute burn toxemia was accompanied by accumulation of the molecules in blood serum of the patients with burns; amount of these molecules correlated with a severity of burn trauma. The "middle mass molecules" were effectively eliminated after haemosorption on a charcoal sorbent SKN.2M. The rate of the "middle mass molecules" elimination in haemosorption correlated with improvement of the patients clinical state, with a decrease in symptoms of intoxication; manifestations of acute psychosis were also decreased.
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Markelov, I. M., Vikhriev, B. S., Tupikova, Z. A., Kuznetsova, L. A. (1983). Content of middle mass molecules in blood serum of patients with burns after hemosorption treatment. Voprosy Meditsinskoi Khimii, 29(3), 105-108.
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