VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Cloning in bacterial and yeast vectors of the hepatitis B virus genome

   
Zhdanov V.M., Granovskiĭ N.N., Kovgan A.A., Drynov I.D., Viazov S.O.
PubMed Id: 6308905
Year: 1983  Volume: 29  Issue: 3  Pages: 4-8
Hepatitis B viral genome was cloned simultaneously with bacterial plasmides pBR 325 and pBR 322. Recombinant plasmides were constructed, containing DNA of hepatitis B virus as well as capable to replication in bacterial and yeast cells. Replication of one of these plasmides was possible if it integrated with chromosomal DNA of yeast target-cells; the other plasmides had a capacity to autonomous replication in yeast cells.
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Zhdanov V.M., Granovskiĭ N.N., Kovgan A.A., Drynov I.D., Viazov S.O. (1983) Voprosy meditsinskoi khimii, 29(3), 4-8.
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