VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Correlation of lactate dehydrogenase activity and its isoenzyme composition in the liver and blood serum in experimental myocardial infarction

   
Prashkiavichius A.K., Lukoshiavichius L.Yu., Grigaliunene V.I., Shatinskene R.R.
PubMed Id: 6649534
Year: 1983  Volume: 29  Issue: 5  Pages: 58-62
After ligation of coronary artery an initial increase in LDH activity in liver tissue was followed by its decrease. Minimal enzymatic activity in liver tissue correlated with maximal activity in blood serum within 1-3 days. Among LDH isoenzymes the "pure" fractions were most markedly altered: LDH1 was decreased in liver tissue and increased in blood serum, LDH5 was increased in the both tissues within later periods after normalization of total activity. Enzymatic activity of LDH, LDH1 and LDH5 was shown to correlate in liver tissue and blood serum.
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Prashkiavichius, A. K., Lukoshiavichius, L. Yu., Grigaliunene, V. I., Shatinskene, R. R. (1983). Correlation of lactate dehydrogenase activity and its isoenzyme composition in the liver and blood serum in experimental myocardial infarction. Voprosy meditsinskoi khimii, 29(5), 58-62.
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