VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Concentration of hormones in the blood of patients with diseases of the gastrointestinal tract in the postoperative period and the effect of hemosorption

   
Bobkov A.I., Semavin I.E., Muratov N.F., Semenova V.V., Pospelov V.V.
PubMed Id: 6367209
Year: 1983  Volume: 29  Issue: 6  Pages: 39-44
Concentrations of cortisol, renin, insulin, thyrocalcitonin were increased and those of triiodothyronine and testosterone were decreased within 1-2 days of a postoperative period. The degree of impairment of content of the hormones correlated with severity of the disease (the most distinct alterations were noted in fatal outcome). Normalization of the hormonal patterns within the first week indicated the favourable course of the disease. In generalized pyoperitoneum a number of hormones wer eliminated from blood after haemosorption: cortisol, aldosterone, triiodothyronine, dehydroepiandrosterone, insulin, thyrotropic hormone, testosterone. The content of adrenal gland hormones was rapidly restored. Other hormones (insulin, thyrotropic hormone, testosterone) apparently had to be administered in the course of therapy. Increases in renin activity, in content of blood somatotropin and thyrocalcitonin appear to be adaptive reactions in response to elimination during haemosorption of a number of biologically active substances.
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Bobkov, A. I., Semavin, I. E., Muratov, N. F., Semenova, V. V., Pospelov, V. V. (1983). Concentration of hormones in the blood of patients with diseases of the gastrointestinal tract in the postoperative period and the effect of hemosorption. Voprosy Meditsinskoi Khimii, 29(6), 39-44.
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