VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Polyadenylated RNA and poly-A segments in the splenic cells of mice with virus-induced Rauscher leukemia

   
Smirnova I.A., Nakonechnyĭ N.V.
PubMed Id: 6199896
Year: 1983  Volume: 29  Issue: 6  Pages: 63-69
In spleen cells of mice with Rauscher++ leukosis polyadenilation of RNA was impaired: an increase in content of Gya poly(A)+ RNA and a change in the composition of poly-A-segments were observed. In DNA of leukemic and normal cells dA-fragments were found content of which was increased in leukemic cells as compared with normal ones. Leukemic transformation appears to be accompanied by appearance of the additional poly-A-fragments in the cells.
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Smirnova, I. A., Nakonechnyĭ, N. V. (1983). Polyadenylated RNA and poly-A segments in the splenic cells of mice with virus-induced Rauscher leukemia. Voprosy Meditsinskoi Khimii, 29(6), 63-69.
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