VOPROSY MEDITSINSKOI KHIMII (ISSN 0042-8809)

Effect of vitamin A deficiency in mice on the formation of specific cytolytic T-lymphocytes

   
Sergeev A.V.
PubMed Id: 6231774
Year: 1984  Volume: 30  Issue: 1  Pages: 55-59
Content of retinol, retinyl acetate and retinyl palmitate was studied by means of high pressure liquid chromatography, in liver tissue of mice, kept on a vitamin A-free diet during various periods of time. Cell proliferative activity and formation of specific T-killers were distinctly inhibited in mixed culture of lymphocytes from spleen tissue of A-avitaminous animals. Proliferative and cytolytic activity of the stimulated lymphocytes might be corrected by means of retinoic acid and retinyl acetate in vitro and in vivo.
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Sergeev A.V. (1984) Voprosy meditsinskoi khimii, 30(1), 55-59.
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